A report entitled "Formyl Peptide Receptor-1 Blockade Prevents Receptor Regulation by Mitochondrial Danger-Associated Molecular Patterns and Preserves Neutrophil Function After Trauma" has been published in Crit Care Med 2020 Feb;48(2):e123-e132, doi: 10.1097/CCM.0000000000004094, PMID: 31939811. The work showed that mitochondrial formylated peptides act as DAMPs …
read moreOregon Innovation Fund SBIR Matching Grant awarded to mAbDx
The Oregon Business Development Department has awarded a $50,000 Oregon Innovation Fund SBIR Matching Grant (contract # C2018319) to mAbDx to support work on their SBIR funded project "Novel, Simple and Rapid Point‐of‐Care Lateral Flow Immunoassays for Diagnosis of Zika Virus Infection." For additional information on the award …
read morePublication of new research on the mechanism of mitochondrial DAMPs (Damage Associated Molecular Patterns) involved in SIRS (the Systemic Inflammatory Response Syndrome)
A combination of immunochemical, biochemical, bioinformatic and in vitro analysis of human neutrophil responses to mitochondrial DAMPs was used to demonstrate evolutionary similarity of five mitochondrial DNA-encoded, formylated peptides (mtFPs) to the canonical inflammatory bacterial peptide fMLF. Analysis of plasma from trauma patients showed that active mtFPs appear to circulate …
read moreCongressman Peter DeFazio applauds SBIR grant awarded to mAbDx to accelerate development of an easy-to-use, point-of-care diagnostic test for Zika virus
U.S. House of Representatives Congressman Peter DeFazio issued a press release today applauding a highly competitive federal research grant awarded to mAbDx. "A small federal investment like an SBIR grant can make a big difference in advancing local innovation and making a positive global impact," said Rep. DeFazio. "This …
read moremAbDx and Oregon State University (OSU) announce new aquaculture research supported by the National Oceanic and Atmospheric Administration (NOAA)
The aquaculture project aims to make oysters safer to eat by developing a rapid diagnostic test for harmful bacteria known as Vibrio parahaemolyticus and by using probiotics isolated at OSU to reduce levels of the bacteria in oysters without altering their texture and consistency. V. parahaemolyticus is a human pathogen …
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