A report entitled "Formyl Peptide Receptor-1 Blockade Prevents Receptor Regulation by Mitochondrial Danger-Associated Molecular Patterns and Preserves Neutrophil Function After Trauma" has been published in Crit Care Med 2020 Feb;48(2):e123-e132, doi: 10.1097/CCM.0000000000004094, PMID: 31939811. The work showed that mitochondrial formylated peptides act as DAMPs …
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Oregon Innovation Fund SBIR Matching Grant awarded to mAbDx
The Oregon Business Development Department has awarded a $50,000 Oregon Innovation Fund SBIR Matching Grant (contract # C2018319) to mAbDx to support work on their SBIR funded project "Novel, Simple and Rapid Point‐of‐Care Lateral Flow Immunoassays for Diagnosis of Zika Virus Infection." For additional information on the award …
read morePublication of new research on the mechanism of mitochondrial DAMPs (Damage Associated Molecular Patterns) involved in SIRS (the Systemic Inflammatory Response Syndrome)
A combination of immunochemical, biochemical, bioinformatic and in vitro analysis of human neutrophil responses to mitochondrial DAMPs was used to demonstrate evolutionary similarity of five mitochondrial DNA-encoded, formylated peptides (mtFPs) to the canonical inflammatory bacterial peptide fMLF. Analysis of plasma from trauma patients showed that active mtFPs appear to circulate …
read moreCongressman Peter DeFazio applauds SBIR grant awarded to mAbDx to accelerate development of an easy-to-use, point-of-care diagnostic test for Zika virus
U.S. House of Representatives Congressman Peter DeFazio issued a press release today applauding a highly competitive federal research grant awarded to mAbDx. "A small federal investment like an SBIR grant can make a big difference in advancing local innovation and making a positive global impact," said Rep. DeFazio. "This …
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