The mAbDx Vibriosis RapidTest was used to help demonstrate that Vibrio coralliilyticus may be causing coinfections that exacerbate existing SCTLD lesions, and therefore may contribute to intraspecific differences observed between colonies. The study shows the potential of the Vibriosis RapidTest as a diagnostic tool capable of tracking the pathogen involved …
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New research published on the mechanism of mitochondrial DAMPs (Damage Associated Molecular Patterns) involved in SIRS (the Systemic Inflammatory Response Syndrome)
A report entitled "Formyl Peptide Receptor-1 Blockade Prevents Receptor Regulation by Mitochondrial Danger-Associated Molecular Patterns and Preserves Neutrophil Function After Trauma" has been published in Crit Care Med 2020 Feb;48(2):e123-e132, doi: 10.1097/CCM.0000000000004094, PMID: 31939811. The work showed that mitochondrial formylated peptides act as DAMPs …
read moreOregon Innovation Fund SBIR Matching Grant awarded to mAbDx
The Oregon Business Development Department has awarded a $50,000 Oregon Innovation Fund SBIR Matching Grant (contract # C2018319) to mAbDx to support work on their SBIR funded project "Novel, Simple and Rapid Point‐of‐Care Lateral Flow Immunoassays for Diagnosis of Zika Virus Infection." For additional information on the award …
read morePublication of new research on the mechanism of mitochondrial DAMPs (Damage Associated Molecular Patterns) involved in SIRS (the Systemic Inflammatory Response Syndrome)
A combination of immunochemical, biochemical, bioinformatic and in vitro analysis of human neutrophil responses to mitochondrial DAMPs was used to demonstrate evolutionary similarity of five mitochondrial DNA-encoded, formylated peptides (mtFPs) to the canonical inflammatory bacterial peptide fMLF. Analysis of plasma from trauma patients showed that active mtFPs appear to circulate …
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